Pei QUN;Yatao HAN;Zhe LIU;Fang XIAO;Yongxia KE;Yunzhang XU;Yuan LIU;[Objectives]To determine the content of inorganic elements in Leontopodium franchetii Beauv. from different production areas, and provide a reference for quality control, safety assessment, and clinical application of L. franchetii Beauv.. [Methods] The contents of Al, B, Ba, Ca, Cd, Cu, Fe, K, Mn, Mo, Na, Ni, P, Pb, Si, Sn, Sr, Ti, V, Zn, Hg, Cr in the sample of L. franchetii Beauv. were determined by the wet digestion and technique of inductively coupled plasma optical emission spectrometry(ICP-OES), and the principal component analysis was carried out for the determination results. [Results] A total of 20 inorganic elements were detected from the samples of L. franchetii Beauv. from different production areas, among which the contents of Ca, Al, P and Fe were higher. There were significant differences among different elements, and samples of different production areas show similar distribution patterns of main elements. Correlation analysis shows that 17 elements had an extremely significant positive correlation and 19 elements had a significant positive correlation. According to the principal component analysis, B, Ca, K, Mn, Mo, Pb, Sn, Sr, Fe, Ni, Ti, V, Zn, Al, and Cd were characteristic inorganic elements of L. franchetii Beauv. [Conclusions] This method is simple, rapid and accurate, and can be used for the analysis and determination of inorganic elements in L. franchetii Beauv., and provides a theoretical basis for better development and utilization of L. franchetii Beauv.
2019年02期 v.10 6-9+13页 [查看摘要][在线阅读][下载 284K] Fulin YAN;Tiantian YIN;[Objectives] To identify chemical constituents and antitumor activities of walnut green husk. [Methods] The column chromatography and recrystallization were used to isolate 13 compounds from walnut green husk, and their structures were identified by modern spectroscopy. [Results] The 13 kinds of compounds isolated from walnut green husk were identified as 3, 5-dimethoxy-4-hydroxy benzene carbonic-7-O-β-D-pyranglucose(1), myricananin F(2), β-stitosterol(3), oleanolic acid(4), regiolone(5), asiatic acid(6), hederagenin(7), β-daucosterin(8),(4 R)-4,8-dihydroxy-α-tetralone-4-O-β-D-glucopyranoside(9), 3β, 23-dihydroxy-urs-12-en-28-oic acid(10), ursolic acid(11), syringc acid(12), and Juglanoside B(13). Among these, compounds 1, 2, 6, 7, 9, and 10 were all isolated from this genus of plant for the first time. [Conclusions] Through screening for antitumor activity in vitro, it was found that compound 4 showed strong growth inhibitory activity against the proliferation of human hepatoma cells(HepG-2), and compound 9 had certain growth inhibitory activity against the proliferation of human breast cancer cells(MCF-7).
2019年02期 v.10 17-20+24页 [查看摘要][在线阅读][下载 186K]