Medicinal Plant

2012, v.3(02) 48-50

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Effect of Four Taste Tibet Inula Root Soft Capsule on Immunodeficiency Mice Model Induced by Cyclophosphamide
Effect of Four Taste Tibet Inula Root Soft Capsule on Immunodeficiency Mice Model Induced by Cyclophosphamide

摘要(Abstract):

[Objective] To study the effect of four-taste Tibet inula root soft capsule on the immunologic function of immunodeficiency mice model induced by cyclophosphamide.[Method] Kunming mice were divided into blank group,model group,four taste Tibet inula root soft capsule group(low-dose and high-dose) and positive medicine group(levamisole hydrochloride tablets).After having been treated with the corresponding dose of drug,the phagocytic percentage and phagocytic index of peritoneal macrophage in immunodeficiency mice model induced by cyclophosphamide were observed.Effects of generated hemolysin antibody and drug on the mice delayed-type hypersensitivity induced by DNFB were analyzed by hemolysin antibody measurement method.[Result] Compared with model group,four taste Tibet inula root soft capsule could significantly enhance the phagocytic percentage and phagocytic index of peritoneal macrophage in immunodeficiency mice,and promote the generation of hemolysin antibody from body.In the test,the difference in the weight between left and right ears was significant in mice with delayed-type hypersensitivity,which was significantly higher than that of mice in model group and control group,having statistical difference.[Conclusion] Four taste Tibet inula root soft capsule could significantly enhance the immune function of immunodeficiency mice induced by cyclophosphamide.

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基金项目(Foundation): Supported by the Project of Qinghai Science & Technology Department (2010-Z-714)

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