Medicinal Plant

2013, v.4(10) 1-4

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Inhibition Effects of Total Saponins from Panax japonicas Cultured Cells on Adjuvant Arthritis Rat
Inhibition Effects of Total Saponins from Panax japonicas Cultured Cells on Adjuvant Arthritis Rat

Yuping LIU;Jinping WANG;Zhigang GUO;

摘要(Abstract):

[Objective]To investigate treatment effects of total Saponins from Panax japonicas cultured cells on the rat adjuvant inflammation.[Methods]Constructing the pathological model using male AA rats,by proinflammatory before and after oral administration,to study the total saponins of Panax japonicus in rat primary and secondary adjuvant arthritis prevention and treatment effect.[Results]The total Saponins isolated from Panax japonicas cultured cells can prevent and significantly reduce the AA rat adjuvant arthritis of primary lesions.Panax japonicus saponins can also well treat and alleviate adjuvant arthritis secondary lesions.The effective dose of total saponins of Panax japonicus was 35-140 mg/kg.[Conclusion]Total Saponins extracted from Panax japonicas cultured cells have good anti-inflammatory effects as nature Panax japonicus extract.

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作者(Author): Yuping LIU;Jinping WANG;Zhigang GUO;

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