Medicinal Plant

2013, v.4(09) 56-57

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Advances in Pharmacological Activity of Febrifugine and Its Derivatives
Advances in Pharmacological Activity of Febrifugine and Its Derivatives

Zhiting GUO;Jianping LIANG;Ruofeng SHANG;Wenzhu GUO;Yu LIU;

摘要(Abstract):

The herbal Dichroa febrifuga Lour is the dried roots of Saxifragaceae plant species Dichroa febrifuga Lour that are endowed with the efficacies of inducing vomiting,insecticide,anti-malaria and relieving heat.It has been broadly applied for treating malaria in folk.We reviewed the advances in pharmacological activity of effective component febrifugine in Dichroa febrifuga Lour and its derivatives,and found that Dichroa febrifuga Lour has been documented effective in antitumor,anti-coccidium,anti-scar,anti-malaria,and the treatment of diabetes mellitus and osteoporosis as well.On the basis of this,we proposed to develop safe and efficient derivatives continuously by structural modification and perform immune study and their antitumor activity.

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基金项目(Foundation): Supported by Central Public-interest Scientific Institution Basal ResearchFund(No.1610322011004)

作者(Author): Zhiting GUO;Jianping LIANG;Ruofeng SHANG;Wenzhu GUO;Yu LIU;

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