Medicinal Plant

2012, v.3(04) 45-47+50

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Pilot Study on Serum Pharmacochemistry of Extract of Citrus reticulata 'Chachi' Peel
Pilot Study on Serum Pharmacochemistry of Extract of Citrus reticulata ‘Chachi’ Peel

摘要(Abstract):

[Objective] To study the serum pharmacochemistry of extract from Citrus reticulata 'Chachi' Peel. [Method] Based on the establishment of HPLC fingerprints of extract of C. reticulata peel, the constituents absorbed into blood were determined by comparing HPLC fingerprints of the methanol extract of C. reticulata peel, medicated plasma with extract of C. reticulata peel and blank serum. [Result] Seventeen compounds absorbed into blood were found in medicated serum, among which five were original constituents of extract from C. reticulata peel and the other might be metabolites of the original constituents. [Conclusion] Polymethoxylated flavones, nobiletin and hesperetin which are absorbed into blood might be bioactive components of extract of C. reticulata peel. Further studies on them will help clarify the bioactive constituents and functional food factors of extract from C. reticulata peel.

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基金项目(Foundation): Supported by the Enterprise Technological Innovative Project of Science,Technology,Industry,Trade and Information Bureau of Zhuhai City [(2009) 414];; Undergraduate Innovative Experimental Project of Department of Education of Guangdong Province (1057310008)

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